|
|
RTECS Number |
DJ3675000 |
Chemical Name |
Benzo(a)pyrene |
CAS Registry Number |
50-32-8 |
Last Updated |
200811 |
Data Items Cited |
708 |
Molecular Formula |
C20-H12 |
Molecular Weight |
252.32 |
Wiswesser Line Notation |
L D6 B6666 2AB TJ |
Compound Descriptor |
Tumorigen Mutagen Human Primary Irritant Reproductive Effector |
- Synonyms/Trade Names
- 3,4-BP
3,4-Benz(a)pyrene 3,4-Benzopirene 3,4-Benzopyrene 3,4-Benzpyren 3,4-Benzpyrene 3,4-Benzypyrene 6,7-Benzopyrene B(a)P BP BaP Benz(a)pyrene Benzo(d,e,f)chrysene Coal tar pitch volatiles: benzo(a)pyrene RCRA waste number U022
|
Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Reaction Severity |
Reference |
Standard Draize test
|
Administration onto the skin
|
Rodent - mouse
|
14 ug
|
Mild
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 4,333,1978
|
|
Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Toxic Effects |
Reference |
LD50 - Lethal dose, 50 percent kill
|
Subcutaneous
|
Rodent - rat
|
50 mg/kg
|
Details of toxic effects not reported other than lethal dose value
|
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 69,103,1967
|
LDLo - Lowest published lethal dose
|
Intraperitoneal
|
Rodent - mouse
|
500 mg/kg
|
Details of toxic effects not reported other than lethal dose value
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 23,288,1972
|
LDLo - Lowest published lethal dose
|
Intrarenal
|
Amphibian - frog
|
9 mg/kg
|
Details of toxic effects not reported other than lethal dose value
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 24,1969,1964
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
100 mg/kg
|
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects
|
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 39,541,2001
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
40 mg/kg
|
Liver - change in gall bladder structure or function
Liver - other changes
Biochemical - Metabolism (Intermediary) - other
|
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,1049,1968
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
100 mg/kg
|
Reproductive - Maternal Effects - ovaries, fallopian tubes
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 5,379,1991
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
80 mg/kg
|
Reproductive - Maternal Effects - oogenesis
Reproductive - Maternal Effects - ovaries, fallopian tubes
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 28,133,1979
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
100 mg/kg
|
Reproductive - Maternal Effects - oogenesis
Reproductive - Maternal Effects - ovaries, fallopian tubes
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 28,133,1979
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
80 mg/kg
|
Reproductive - Maternal Effects - oogenesis
Reproductive - Maternal Effects - ovaries, fallopian tubes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 53,249,1980
|
TDLo - Lowest published toxic dose
|
Unreported
|
Non-mammalian species
|
2 mg/kg
|
Immunological Including Allergic - decrease in humoral immune response
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,174,2003
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Non-mammalian species
|
3 mg/kg
|
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 192,45,2003
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
50 mg/kg
|
Blood - changes in bone marrow (not otherwise specified)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 193,84,2003
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
25 mg/kg
|
Brain and Coverings - other degenerative changes
Behavioral - changes in motor activity (specific assay)
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 129,33,2002
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
266.7 ng/kg
|
Brain and Coverings - other degenerative changes
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 133,211,2002
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
50 mg/kg
|
Liver - other changes
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 143-144,55,2003
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - rat
|
12 mg/kg
|
Lungs, Thorax, or Respiration - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 143,223,2003
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - rat
|
12 mg/kg
|
Lungs, Thorax, or Respiration - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 150,179,2004
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
50 mg/kg
|
Lungs, Thorax, or Respiration - other changes
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 202,244,2005
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - rat
|
10.5 mg/kg
|
Lungs, Thorax, or Respiration - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - cytochrome oxidases (including oxidative phosphorylation)
Biochemical - Metabolism (Intermediary) - other
|
JAPTO* Journal of Applied Toxicology (John Wiley & Sons, Ltd., Oldlands Way Bognor Regis West Sussex, PO22 9SA England) V.1- 1981- Volume(issue)/page/year: 24,249,2004
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Non-mammalian species
|
2 mg/kg
|
Immunological Including Allergic - decrease in humoral immune response
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,230,2001
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
500 mg/kg
|
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
Biochemical - Metabolism (Intermediary) - other
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,277,2001
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
12.5 mg/kg
|
Brain and Coverings - other degenerative changes
Behavioral - changes in motor activity (specific assay)
Biochemical - Neurotransmitters or modulators (putative) - dopamine in striatum
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,370,2002
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
25 mg/kg
|
Sense Organs and Special Senses (Eye) - lacrimation
Behavioral - changes in motor activity (specific assay)
Behavioral - alteration of classical conditioning
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,379,2001
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
25 mg/kg
|
Behavioral - alteration of operant conditioning
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,379,2001
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
100 mg/kg
|
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 211,132,2005
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
7570 ug/kg
|
Immunological Including Allergic - decrease in humoral immune response
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 78,397,2004
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
50 mg/kg
|
Blood - changes in bone marrow (not otherwise specified)
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 213,105,2006
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
25 mg/kg
|
Brain and Coverings - other degenerative changes
Behavioral - changes in motor activity (specific assay)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
|
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 26,427,2006
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
125 mg/kg
|
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
|
HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 24,149,2005
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
20 mg/kg/24H
|
Biochemical - Metabolism (Intermediary) - other
|
PHTOEH Pharmacology and Toxicology (Copenhagen). (Munksgaard International Pub., POB 2148, DK-1016 Copenhagen K, Denmark) V.60- 1987- Volume(issue)/page/year: 92,242,2003
|
|
OTHER MULTIPLE DOSE TOXICITY DATA |
Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Toxic Effects |
Reference |
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
9 gm/kg/90D (intermittent)
|
Kidney/Ureter/Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 30,323,1996
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
2250 mg/kg/5W (intermittent)
|
Blood - changes in spleen
Immunological Including Allergic - decreased immune response
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 148,126,1998
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
400 mg/kg/2W (intermittent)
|
Immunological Including Allergic - decrease in humoral immune response
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 3,86,1983
|
TDLo - Lowest published toxic dose
|
Unreported
|
Rodent - mouse
|
180 mg/kg/12D (intermittent)
|
Immunological Including Allergic - uncharacterized
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 48,13,1999
|
TDLo - Lowest published toxic dose
|
Oral
|
Non-mammalian species
|
171 mg/kg/30D (continuous)
|
Endocrine - androgenic
Endocrine - estrogenic
Related to Chronic Data - changes in ovarian weight
|
MAERE* Marine Environmental Research. (Kidlington, Oxford : Elsevier) V. 1- 1978- Volume(issue)/page/year: 24,179,1988
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
75 ug/m3/10D (intermittent)
|
Endocrine - estrogenic
Endocrine - other changes
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 16,801,2002
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
1000 mg/kg/10D (intermittent)
|
Liver - changes in liver weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,132,2003
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
75 ug/m3/10D (intermittent)
|
Endocrine - changes in luteinizing hormone
Endocrine - androgenic
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 17,527,2003
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
2.5 mg/kg/5W (intermittent)
|
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 15,479,2001
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
75 ug/m3/6H/60D (intermittent)
|
Liver - other changes
Endocrine - androgenic
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,325,2003
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
100 ug/m3/4H/10D (intermittent)
|
Reproductive - Maternal Effects - ovaries, fallopian tubes
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,338,2003
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
200 mg/kg/15D (intermittent)
|
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Immunological Including Allergic - increase in cellular immune response
Immunological Including Allergic - increase in humoral immune response
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 199,261,2004
|
TDLo - Lowest published toxic dose
|
Oral
|
Mammal - species unspecified
|
87.5 mg/kg/7D (intermittent)
|
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,195,2005
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
5040 mg/kg/12W (continuous)
|
Liver - other changes
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,116,2005
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
1120 mg/kg/16W (intermittent)
|
Kidney/Ureter/Bladder - changes primarily in glomeruli
Kidney/Ureter/Bladder - proteinuria
Kidney/Ureter/Bladder - other changes
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 78,90,2004
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - mouse
|
8 mg/kg/5W (intermittent)
|
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Immunological Including Allergic - increase in humoral immune response
Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 157,31,2005
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
8.4 mg/kg/2W (intermittent)
|
Liver - other changes
Liver - changes in liver weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 44,179,2004
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
3750 mg/kg/30D (intermittent)
|
Blood - changes in bone marrow (not otherwise specified)
Immunological Including Allergic - decreased immune response
Related to Chronic Data - death
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 78,347,2004
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
375 mg/kg/30D (intermittent)
|
Immunological Including Allergic - decreased immune response
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 78,347,2004
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
3 mg/kg/3D (intermittent)
|
Related to Chronic Data - changes in uterine weight
|
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 46,454,2004
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
0.6 mg/kg/30D (intermittent)
|
Blood - other hemolysis with or without anemia
Blood - changes in other cell count (unspecified)
Blood - changes in erythrocyte (RBC) count
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,141,2001
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
600 mg/kg/30D (intermittent)
|
Endocrine - changes in spleen weight
Blood - changes in spleen
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,141,2001
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
25000 mg/m3/10D (intermittent)
|
Endocrine - other changes
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
Reproductive - Paternal Effects - testes, epididymis, sperm duct
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,273,2001
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
50 mg/kg/5W (intermittent)
|
Kidney/Ureter/Bladder - other changes in urine composition
Kidney/Ureter/Bladder - other changes
Kidney/Ureter/Bladder - changes in kidney weight
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,310,2001
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
80 mg/kg/8W (intermittent)
|
Kidney/Ureter/Bladder - changes primarily in glomeruli
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,312,2001
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
160 mg/kg/16W (intermittent)
|
Kidney/Ureter/Bladder - proteinuria
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,312,2001
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
0.05 mg/m3/4H/10D (intermittent)
|
Reproductive - Maternal Effects - oogenesis
Reproductive - Maternal Effects - ovaries, fallopian tubes
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,369,2002
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
200 mg/kg/5D (intermittent)
|
Lungs, Thorax, or Respiration - other changes
Biochemical - Metabolism (Intermediary) - other proteins
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,382,2001
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
156 mg/kg/4W (intermittent)
|
Immunological Including Allergic - decrease in cellular immune response
Immunological Including Allergic - increase in humoral immune response
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 211,107,2005
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
52987 ug/kg/7D (intermittent)
|
Endocrine - changes in spleen weight
Endocrine - changes in thymus weight
Blood - changes in spleen
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 78,397,2004
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
3750 mg/kg/30D (intermittent)
|
Blood - changes in bone marrow (not otherwise specified)
Related to Chronic Data - death
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 90,371,2006
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
75 ug/m3/60D (intermittent)
|
Endocrine - changes in luteinizing hormone
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
Related to Chronic Data - changes in testicular weight
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 90,429,2006
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
50 mg/kg/5W (intermittent)
|
Kidney/Ureter/Bladder - renal function tests depressed
Kidney/Ureter/Bladder - changes in kidney weight
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 164,214,2006
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
20 mg/kg/2W (intermittent)
|
Kidney/Ureter/Bladder - proteinuria
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 164,214,2006
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
30 mg/kg/3D (intermittent)
|
Biochemical - Neurotransmitters or modulators (putative) - dopamine at other sites
|
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- Volume(issue)/page/year: 28,860,2007
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
200 mg/kg/10D (intermittent)
|
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- Volume(issue)/page/year: 28,630,2007
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
0.2 mg/kg/10D (intermittent)
|
Brain and Coverings - other degenerative changes
Behavioral - changes in motor activity (specific assay)
Behavioral - alteration of operant conditioning
|
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- Volume(issue)/page/year: 28,630,2007
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
1200 mg/kg/20W (intermittent)
|
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
|
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 33,609,2005
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
75.696 mg/kg/3D (intermittent)
|
Lungs, Thorax, or Respiration - other changes
Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects
|
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 81,169,2007
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
78 mg/kg/14D (intermittent)
|
Endocrine - changes in spleen weight
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 226,46,2008
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
26 mg/kg/2D (intermittent)
|
Blood - changes in spleen
Immunological Including Allergic - decreased immune response
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 226,46,2008
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
819 mg/kg/13W (continuous)
|
Tumorigenic - increased incidence of tumors in susceptible strains
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 24,613,2003
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
400 mg/kg/4W (intermittent)
|
Gastrointestinal - tumors
Nutritional and Gross Metabolic - weight loss or decreased weight gain
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 24,461,2003
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
400 mg/kg/4W (intermittent)
|
Lungs, Thorax, or Respiration - tumors
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
Biochemical - Metabolism (Intermediary) - lipids including transport
|
BPBLEO Biological and Pharmaceutical Bulletin. (Pharmaceutical Society of Japan, 2-12-15-201 Shibuya Shibuya-ku, Tokyo 150, Japan) V.16- 1993- Volume(issue)/page/year: 30,2268,2007
|
|
Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Toxic Effects |
Reference |
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
15 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Gastrointestinal - tumors
Musculoskeletal - tumors
|
EXPTAX Experimentelle Pathologie (1967-1980). (Jena, Ger. Dem. Rep.) V.1-18, 1967-80. For publisher information, see EXPADD. Volume(issue)/page/year: 18,288,1980
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
16 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 12,65,1958
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - rat
|
455 ug/kg/60D (intermittent)
|
Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 29,159,1980
|
TDLo - Lowest published toxic dose
|
Intravenous
|
Rodent - rat
|
39 mg/kg/6D (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,506,1969
|
TDLo - Lowest published toxic dose
|
Intramuscular
|
Rodent - rat
|
2400 ug/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
|
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: DOE/EV/03140-5
|
TDLo - Lowest published toxic dose
|
Intracerebral
|
Rodent - rat
|
22 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Brain and Coverings - tumors
Tumorigenic - tumors at site of application
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,1927,1969
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - rat
|
1200 ug/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Skin and Appendages - tumors
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,1285,1989
|
TDLo - Lowest published toxic dose
|
Implant
|
Rodent - rat
|
150 ug/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Tumorigenic - tumors at site of application
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 72,733,1984
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
700 mg/kg/75W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Blood - leukemia
|
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(12),14,1980
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - mouse
|
200 ng/m3/6H/13W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(7),23,1982
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
120 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
|
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 71,677,1971
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
28500 ug/kg/19W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
|
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2 Volume(issue)/page/year: 9,297,1987
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
25 ng/kg/110W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
|
ARGEAR Archiv fuer Geschwulstforschung. (VEB Verlag Volk und Gesundheit Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1949- Volume(issue)/page/year: 50,266,1980
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
10 mg/kg
|
Tumorigenic - neoplastic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978- Volume(issue)/page/year: 4,74,1980
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
300 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
Lungs, Thorax, or Respiration - tumors
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 6,569,1980
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
300 mg/kg
|
Tumorigenic - neoplastic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Reproductive - Specific Developmental Abnormalities - respiratory system
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 55,227,1990
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
9 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
480 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
Lungs, Thorax, or Respiration - tumors
|
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 135,84,1970
|
TDLo - Lowest published toxic dose
|
Intravenous
|
Rodent - mouse
|
10 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 1,225,1940
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - mouse
|
200 mg/kg/10W (intermittent)
|
Tumorigenic - neoplastic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
PWPSA8 Proceedings of the Western Pharmacology Society. (Univ. of California Dept. of Pharmacology, Los Angeles, CA 90024) V.1- 1958- Volume(issue)/page/year: 22,269,1979
|
TDLo - Lowest published toxic dose
|
Implant
|
Rodent - mouse
|
200 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 39,761,1979
|
TDLo - Lowest published toxic dose
|
Unreported
|
Rodent - mouse
|
80 mg/kg/8D (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
|
BEBMAE Byulleten' Eksperimental'noi Biologii i Meditsiny. Bulletin of Experimental Biology and Medicine. For English translation, see BEXBAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 88(11),592,1979
|
TDLo - Lowest published toxic dose
|
Rectal
|
Rodent - mouse
|
200 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Blood - leukemia
Gastrointestinal - colon tumors
|
ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 37,77,1980
|
TDLo - Lowest published toxic dose
|
Parenteral
|
Mammal - dog
|
819 mg/kg/26W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 65,921,1980
|
TDLo - Lowest published toxic dose
|
Implant
|
Mammal - dog
|
651 mg/kg/21W (continuous)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - dyspnea
Tumorigenic - tumors at site of application
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 65,921,1980
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Primate - monkey
|
40 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Tumorigenic - tumors at site of application
|
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 127,594,1968
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - rabbit
|
17 mg/kg/57W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
|
HSZPAZ Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie. (Walter de Gruyter, Inc., 200 Saw Mill River Rd., Hawthorne, NY 10532) V.21- 1895/96- Volume(issue)/page/year: 236,79,1935
|
TDLo - Lowest published toxic dose
|
Intravenous
|
Rodent - rabbit
|
30 mg/kg
|
Tumorigenic - neoplastic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
Peripheral Nerve and Sensation - structural change in nerve or sheath
|
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 85,369,1978
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - rabbit
|
145 mg/kg/2Y (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - bronchiogenic carcinoma
Blood - leukemia
|
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 71,197,1980
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - hamster
|
420 mg/kg/21W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
Skin and Appendages - tumors
|
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 65,56,1962
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - hamster
|
9500 ug/m3/4H/96W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Sense Organs and Special Senses (Olfaction) - tumors
Lungs, Thorax, or Respiration - tumors
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 66,575,1981
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - hamster
|
4000 ug/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - bronchiogenic carcinoma
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 32,360,1972
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - hamster
|
64 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 3,231,1977
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - hamster
|
120 mg/kg/17W (intermittent)
|
Tumorigenic - neoplastic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 25,271,1985
|
TDLo - Lowest published toxic dose
|
Implant
|
Rodent - hamster
|
5 mg/kg/22W (continuous)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 47,5202,1987
|
TDLo - Lowest published toxic dose
|
Implant
|
Amphibian - frog
|
45 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Liver - tumors
Kidney/Ureter/Bladder - Kidney tumors
|
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 20,143,1964
|
TD - Toxic dose (other than lowest)
|
Implant
|
Rodent - rat
|
500 ug/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Tumorigenic - tumors at site of application
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 20,97,1983
|
TD - Toxic dose (other than lowest)
|
Administration onto the skin
|
Rodent - mouse
|
12 mg/kg/20D (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 6,1483,1985
|
TD - Toxic dose (other than lowest)
|
Intratracheal
|
Rodent - rat
|
200 mg/kg/15W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
|
31BYAP "Experimental Lung Cancer: Carcinogenesis and Bioassays, International Symposium, 1974," Karbe, E., and J.F. Park, eds., Springer-Verlag New York, Inc., 1974 Volume(issue)/page/year: -,199,1974
|
TD - Toxic dose (other than lowest)
|
Administration onto the skin
|
Rodent - mouse
|
26 mg/kg/65W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
|
AJPAA4 American Journal of Pathology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1925- Volume(issue)/page/year: 102,381,1981
|
TD - Toxic dose (other than lowest)
|
Rectal
|
Rodent - mouse
|
560 mg/kg/14W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Skin and Appendages - tumors
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 20,117,1983
|
TD - Toxic dose (other than lowest)
|
Subcutaneous
|
Rodent - mouse
|
8 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 12,657,1952
|
TD - Toxic dose (other than lowest)
|
Intratracheal
|
Rodent - hamster
|
360 mg/kg/36W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 32,28,1972
|
TD - Toxic dose (other than lowest)
|
Intramuscular
|
Rodent - rat
|
3150 ug/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
|
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 21,72,1980
|
TD - Toxic dose (other than lowest)
|
Administration onto the skin
|
Rodent - mouse
|
18 mg/kg/73W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
|
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 38,149,1981
|
TD - Toxic dose (other than lowest)
|
Subcutaneous
|
Rodent - mouse
|
12 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
|
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 62,309,1971
|
TDLo - Lowest published toxic dose
|
Intratracheal
|
Rodent - mouse
|
0.5 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 477,41,2001
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
480 mg/kg/32W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 163,1,2001
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
20 mg/kg/5D (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - other changes
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 159,113,2000
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
240 mg/kg/12D (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 21,179,2000
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
32.3 mg/kg/8D (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Liver - tumors
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 137,137,1999
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
38 ug/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Liver - tumors
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 185,13,2002
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
200 mg/kg
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
|
VOONC* Voprosi oncologii (Questions of oncology. Journal of Petrov's Institute of Oncology, B. Zelenina str, 43a, Spb 197110, Russia) V.1- 1955- Volume(issue)/page/year: -,950,1992
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
1000 ug/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,86,2003
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
14 mg/kg/14W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,86,2003
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
100 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
MOCAE8 Molecular Carcinogenesis. (John Wiley & Sons, 605 Third Avenue, New York, NY 10158) V.1- 1988- Volume(issue)/page/year: 35,93,2002
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
320 mg/kg/4W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Gastrointestinal - tumors
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 144,183,2003
|
TDLo - Lowest published toxic dose
|
Administration onto the skin
|
Rodent - mouse
|
30 mg/kg/10D (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
|
PBBHAU Pharmacology, Biochemistry and Behavior. (ANKHO International Inc., P.O. Box 426, Fayetteville, NY 13066) V.1- 1973- Volume(issue)/page/year: 21,17,1984
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
80 mg/kg/8W (intermittent)
|
Tumorigenic - carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Tumorigenic - increased incidence of tumors in susceptible strains
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 91,1380,2004
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
100 mg/kg
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,186,2002
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
2340 mg/kg/39W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
Blood - lymphoma, including Hodgkin's disease
|
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 33,609,2005
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
400 mg/kg/4W (intermittent)
|
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
|
BPBLEO Biological and Pharmaceutical Bulletin. (Pharmaceutical Society of Japan, 2-12-15-201 Shibuya Shibuya-ku, Tokyo 150, Japan) V.16- 1993- Volume(issue)/page/year: 30,2268,2007
|
|
Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Sex/Duration |
Toxic Effects |
Reference |
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
40 mg/kg
|
female 14 day(s) after conception
|
Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)
Reproductive - Effects on Embryo or Fetus - other effects to embryo
|
NSAPCC Naunyn-Schmiedeberg's Archives of Pharmacology. (Springer Verlag, Heidelberger, Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.272- 1972- Volume(issue)/page/year: 272,89,1972
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
2 gm/kg
|
female 28 day(s) pre-mating
1-22 day(s) after conception
|
Reproductive - Effects on Newborn - stillbirth
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
|
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 20,224,1964
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
1344 mg/kg
|
female 15 day(s) pre-mating - 5 day(s) post-birth
|
Reproductive - Effects on Newborn - live birth index (measured after birth)
|
DOESD6 DOE Symposium Series. (NTIS, 5285 Port Royal Rd., Springfield, VA 22161) No.45- 1978- Volume(issue)/page/year: 54,410,1981
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - rat
|
60 mg/kg
|
female 16-18 day(s) after conception
|
Reproductive - Effects on Newborn - biochemical and metabolic
|
BNEOBV Biology of the Neonate. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.15- 1970- Volume(issue)/page/year: 38,291,1980
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - rat
|
150 mg/kg
|
female 6-8 day(s) after conception
|
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
Reproductive - Effects on Embryo or Fetus - fetal death
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 42,195,1986
|
TDLo - Lowest published toxic dose
|
Intramuscular
|
Rodent - rat
|
2100 ug/kg
|
female 15-19 day(s) after conception
|
Reproductive - Effects on Newborn - behavioral
|
JDPHDH Journal of Developmental Physiology. (Oxford University Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1979- Volume(issue)/page/year: 19,67,1993
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
100 mg/kg
|
female 16 day(s) pre-mating - 5 day(s) post-birth
|
Reproductive - Maternal Effects - oogenesis
|
DOESD6 DOE Symposium Series. (NTIS, 5285 Port Royal Rd., Springfield, VA 22161) No.45- 1978- Volume(issue)/page/year: 54,410,1981
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
1280 mg/kg
|
female 16 day(s) pre-mating - 5 day(s) post-birth
|
Reproductive - Effects on Newborn - germ cell effects (in offspring)
|
DOESD6 DOE Symposium Series. (NTIS, 5285 Port Royal Rd., Springfield, VA 22161) No.45- 1978- Volume(issue)/page/year: 54,410,1981
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
100 mg/kg
|
female 7-16 day(s) after conception
|
Reproductive - Effects on Newborn - delayed effects
|
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 19,37A,1979
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
100 mg/kg
|
multigenerations
|
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
|
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 24,183,1981
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
75 mg/kg
|
female 12-14 day(s) after conception
|
Reproductive - Effects on Newborn - biochemical and metabolic
|
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32,29A,1985
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - mouse
|
100 mg/kg
|
female 7-16 day(s) after conception
|
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
|
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 24,183,1981
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
50 mg/kg
|
female 1 day(s) pre-mating
|
Reproductive - Maternal Effects - oogenesis
|
PPHAD4 Pediatric Pharmacology. (New York, NY) V.1-5, 1980-86. For publisher information, see DPTHDL. Volume(issue)/page/year: 1,143,1980
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
1500 mg/kg
|
male 5 day(s) pre-mating
|
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,712,1981
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
300 mg/kg
|
female 16-18 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - immune and reticuloendothelial system
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 6,569,1980
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
200 mg/kg
|
female 7 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
Reproductive - Specific Developmental Abnormalities - skin and skin appendages
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
|
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 20,365,1979
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
150 mg/kg
|
female 8 day(s) after conception
|
Reproductive - Effects on Newborn - stillbirth
|
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: CONF-771017
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - mouse
|
250 mg/kg
|
female 13-17 day(s) after conception
|
Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)
Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow)
Reproductive - Specific Developmental Abnormalities - immune and reticuloendothelial system
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 42,259,1994
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
160 mg/kg
|
female 12 day(s) after conception
|
Reproductive - Effects on Newborn - live birth index (measured after birth)
Reproductive - Effects on Newborn - biochemical and metabolic
|
PPHAD4 Pediatric Pharmacology. (New York, NY) V.1-5, 1980-86. For publisher information, see DPTHDL. Volume(issue)/page/year: 1,85,1980
|
TDLo - Lowest published toxic dose
|
Subcutaneous
|
Rodent - mouse
|
12 gm/kg
|
multigenerations
|
Reproductive - Specific Developmental Abnormalities - respiratory system
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 55,227,1990
|
TDLo - Lowest published toxic dose
|
Unreported
|
Rodent - mouse
|
40 ug/kg
|
female 1 day(s) pre-mating
|
Reproductive - Maternal Effects - oogenesis
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 76,18,1984
|
TDLo - Lowest published toxic dose
|
Intraperitoneal
|
Rodent - hamster
|
10 mg/kg
|
male 5 day(s) pre-mating
|
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
Reproductive - Paternal Effects - testes, epididymis, sperm duct
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 8,929,1981
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
75 ug/m3
|
female 11-20 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 16,801,2002
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
25 ug/m3
|
female 11-20 day(s) after conception
|
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 16,801,2002
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
25 ug/m3
|
female 11-20 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Effects on Newborn - live birth index (measured after birth)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,125,2003
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
100 ug/m3
|
female 14-17 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,125,2003
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
100 ug/m3
|
female 8-21 day(s) after conception
|
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
Reproductive - Effects on Newborn - other neonatal measures or effects
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72(Suppl 1),338,2003
|
TDLo - Lowest published toxic dose
|
Oral
|
Mammal - species unspecified
|
875 mg/kg
|
female 4-10 day(s) after conception
|
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,195,2005
|
TDLo - Lowest published toxic dose
|
Oral
|
Mammal - species unspecified
|
87.5 mg/kg
|
female 4-10 day(s) after conception
|
Reproductive - Effects on Embryo or Fetus - fetal death
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,195,2005
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
0.025 mg/m3
|
female 11-20 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - Central Nervous System
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,335,2002
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
100 ug/m3
|
female 14-17 day(s) after conception
|
Reproductive - Effects on Newborn - biochemical and metabolic
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 60,274,2001
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
25 ug/m3
|
female 10-19 day(s) after conception
|
Reproductive - Effects on Embryo or Fetus - fetal death
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,369,2002
|
TDLo - Lowest published toxic dose
|
Oral
|
Rodent - rat
|
100 ug/kg
|
female 14-17 day(s) after conception
|
Reproductive - Effects on Newborn - biochemical and metabolic
|
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- Volume(issue)/page/year: 28,965,2007
|
|
Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Reference |
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
312 ng/plate
|
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 44,131,1984
|
Mutation test systems - not otherwise specified
|
|
Bacteria - Salmonella typhimurium
|
1 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 192,239,1987
|
DNA adduct
|
|
Bacteria - Salmonella typhimurium
|
147 gm/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 109,183,1983
|
Phage inhibition capacity
|
|
Bacteria - Salmonella typhimurium
|
3900 pmol/plate
|
PPTCBY Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. (Japan Scientific Soc. Press, 6-2-10 Hongo, Bunkyo-ku, Tokyo 113, Japan) 1st- 1971- Volume(issue)/page/year: 9,337,1979
|
Mutation in microorganisms
|
|
Bacteria - Escherichia coli
|
1 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 60,395,1979
|
Mutation test systems - not otherwise specified
|
|
Bacteria - Escherichia coli
|
700 pmol/tube
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 79,5971,1982
|
Mutation in microorganisms
|
|
Bacteria - Escherichia coli
|
200 nmol/plate
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 135,87,1984
|
DNA repair
|
|
Bacteria - Escherichia coli
|
70 ug/well
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,53,1977
|
DNA damage
|
|
Bacteria - Escherichia coli
|
500 mg/L
|
BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 103,275,1965
|
Phage inhibition capacity
|
|
Bacteria - Escherichia coli
|
400 ng/plate
|
CSHCAL Cold Spring Harbor Conferences on Cell Proliferation. (Cold Spring Harbor, NY) V.1-10, 1974-83. Volume(issue)/page/year: 4,1451,1977
|
Mutation in microorganisms
|
|
Bacteria - Bacillus subtilis
|
5 gm/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,19,1977
|
DNA damage
|
|
Bacteria - Bacillus subtilis
|
200 ug/disc
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,175,1981
|
DNA adduct
|
|
Microorganism - not otherwise specified
|
3 umol/L
|
PNCCA2 Proceedings, National Cancer Conference. (Philadelphia, PA) V.1-7, 1949-72. For publisher information, see CANCAR. Volume(issue)/page/year: 5,39,1965
|
Unscheduled DNA synthesis
|
|
Microorganism - not otherwise specified
|
1 mg/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 2,417,1981
|
DNA inhibition
|
|
Microorganism - not otherwise specified
|
200 ug/L
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 74,1378,1977
|
DNA inhibition
|
|
Microorganism - not otherwise specified
|
100 ug/L
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 74,1378,1977
|
DNA adduct
|
|
Microorganism - not otherwise specified
|
11 ng/L
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 39,205,1982
|
DNA damage
|
|
Microorganism - not otherwise specified
|
100 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 368,235,1996
|
Specific locus test
|
Oral
|
Insect - Drosophila melanogaster
|
250 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 234,71,1990
|
DNA repair
|
Oral
|
Insect - Drosophila melanogaster
|
100 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 290,175,1993
|
DNA adduct
|
Oral
|
Insect - Drosophila melanogaster
|
1 mmol/L
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 23,171,1994
|
Sex chromosome loss and nondisjunction
|
Parenteral
|
Insect - Drosophila melanogaster
|
5 mmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,302,1973
|
Sex chromosome loss and nondisjunction
|
Oral
|
Insect - Drosophila melanogaster
|
100 umol/L
|
BIZNAT Biologisches Zentralblatt. (VEB Georg Thieme, Postfach 946, Leipzig DDR-7010, Ger. Dem. Rep.) V.1- 1881- Volume(issue)/page/year: 102,271,1983
|
Mutation in microorganisms
|
|
Yeast - Saccharomyces cerevisiae
|
1 gm/L
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,414,1981
|
Mutation in microorganisms
|
|
Yeast - Saccharomyces cerevisiae
|
50 mg/L
|
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 33,1576,1985
|
Gene conversion and mitotic recombination
|
|
Yeast - Saccharomyces cerevisiae
|
10 ug/plate
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,456,1981
|
Sex chromosome loss and nondisjunction
|
|
Yeast - Saccharomyces cerevisiae
|
150 mg/L
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,468,1981
|
Micronucleus test
|
Multiple routes
|
Non-mammalian species
|
1000 ppb
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 390,33,1997
|
Micronucleus test
|
Multiple routes
|
Non-mammalian species
|
10 ppb/8D (continuous)
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8,41,1986
|
Micronucleus test
|
Intraperitoneal
|
Fish - not otherwise specified
|
10 mg/kg
|
CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 47,147,1986
|
Specific locus test
|
Oral
|
Insect - not otherwise specified
|
500 ppm
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 268,155,1992
|
Micronucleus test
|
Multiple routes
|
Non-mammalian species
|
60 ppb
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 292,83,1993
|
DNA adduct
|
Oral
|
Fish - not otherwise specified
|
125 umol/kg/5D (intermittent)
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 427,135,1999
|
DNA adduct
|
|
Non-mammalian species
|
1700 nmol/L
|
GANMAX Gann Monograph. (Tokyo, Japan) No.1-10, 1966-71. For publisher information, see GMCRDC. Volume(issue)/page/year: 6,49,1968
|
DNA adduct
|
Intraperitoneal
|
Fish - not otherwise specified
|
20 mg/kg
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 49,81,1990
|
DNA adduct
|
|
Fish - salmon
Testis
|
5 ug/1H (continuous)
|
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 110,159,1968
|
DNA damage
|
|
Fish - salmon
Cells - not otherwise specified
|
80 umol/L
|
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 23,51,1978
|
DNA damage
|
Intraperitoneal
|
Fish - not otherwise specified
|
125 gm/kg
|
STEVA8 Science of the Total Environment. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1972- Volume(issue)/page/year: 32,13,1983
|
Unscheduled DNA synthesis
|
|
Fish - not otherwise specified
Liver
|
10 umol/L
|
NCIMAV National Cancer Institute, Monograph. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) No.1- 1959- Volume(issue)/page/year: 65,163,1984
|
Unscheduled DNA synthesis
|
|
Fish - not otherwise specified
Liver
|
20 nmol/L
|
HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1981- Volume(issue)/page/year: 4,368,1984
|
Unscheduled DNA synthesis
|
|
Fish - not otherwise specified
Liver
|
1 umol/L
|
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,555,1985
|
Unscheduled DNA synthesis
|
|
Fish - not otherwise specified
Cells - not otherwise specified
|
10 umol/L
|
CBPCEE Comparative Biochemistry and Physiology, C: Pharmacology, Toxicology and Endocrinology. (Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.74- 1983- Volume(issue)/page/year: 86,399,1987
|
Cytogenetic analysis
|
Administration onto the skin
|
Fish - not otherwise specified
|
100 ng/L
|
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 5,261,1981
|
Cytogenetic analysis
|
|
Fish - not otherwise specified
Cells - not otherwise specified
|
100 ug/L/48H
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,181,1982
|
Cytogenetic analysis
|
Multiple routes
|
Non-mammalian species
|
10 ug/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 319,223,1993
|
Mutation in mammalian somatic cells
|
|
Fish - not otherwise specified
Fibroblast
|
5 mg/L
|
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 10,663,1981
|
Micronucleus test
|
|
Human
Cells - not otherwise specified
|
10 mg/L
|
TIVIEQ Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 5,515,1991
|
Micronucleus test
|
|
Human
Lymphocyte
|
50 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 291,93,1993
|
Mutation in microorganisms
|
|
Human
Lymphocyte
|
4 mg/L
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 63,309,1979
|
DNA adduct
|
|
Human
Liver
|
100 nmol/L
|
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 25,117,1984
|
Morphological transformation
|
|
Human
Cells - not otherwise specified
|
10 mg/L
|
ITCSAF In Vitro. (Rockville, MD) V.1-20, 1965-85. For publisher information, see ICDBEO. Volume(issue)/page/year: 17,719,1981
|
Morphological transformation
|
|
Human
Fibroblast
|
3200 ug/L
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 13,119,1981
|
DNA adduct
|
|
Human
Lymphocyte
|
1 umol/L/72H
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 49,6503,1989
|
DNA damage
|
|
Human
Fibroblast
|
10 mg/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 38,1638,1978
|
DNA adduct
|
|
Human
Cells - not otherwise specified
|
1500 nmol/L
|
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 1,3,1980
|
DNA damage
|
|
Human
HeLa cell
|
1500 nmol/L
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,20,1991
|
DNA damage
|
|
Human
Leukocyte
|
500 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 346,49,1995
|
DNA adduct
|
|
Human
Cells - not otherwise specified
|
400 nmol/L
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 78,6251,1981
|
Unscheduled DNA synthesis
|
|
Human
Cells - not otherwise specified
|
1 umol/L
|
TIVIEQ Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 5,377,1991
|
Unscheduled DNA synthesis
|
|
Human
HeLa cell
|
1 mmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 38,2621,1978
|
DNA adduct
|
|
Human
Lung
|
1 umol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,195,1982
|
Unscheduled DNA synthesis
|
|
Human
Liver
|
1 umol/L
|
BANRDU Banbury Report. (Cold Spring Harbor Laboratory, POB 100, Cold Spring Harbor, NY 11724) V.1- 1979- Volume(issue)/page/year: 13,101,1982
|
DNA inhibition
|
|
Human
HeLa cell
|
1500 nmol/L
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,20,1991
|
DNA adduct
|
|
Human
Cells - not otherwise specified
|
4 umol/L
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 18,11,1983
|
Unscheduled DNA synthesis
|
|
Human
Cells - not otherwise specified
|
10 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 122,377,1983
|
Unscheduled DNA synthesis
|
|
Human
Cells - not otherwise specified
|
3 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 140,43,1984
|
Unscheduled DNA synthesis
|
|
Human
Cells - not otherwise specified
|
5 umol/L
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 79,28,1985
|
DNA inhibition
|
|
Human
Fibroblast
|
1 mg/L
|
NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 33,699,1986
|
Unscheduled DNA synthesis
|
|
Human
Mammary gland
|
10 umol/L
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 20,148,1992
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
150 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 441,215,1999
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
40 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 467,21,2000
|
Cytogenetic analysis
|
|
Human
Fibroblast
|
40 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,297,1977
|
Cytogenetic analysis
|
|
Human
Leukocyte
|
1 mg/L
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 30,103,1974
|
Cytogenetic analysis
|
|
Human
Lymphocyte
|
2400 ug/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 113,239,1983
|
Sister chromatid exchange
|
|
Human
Leukocyte
|
50 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 346,49,1995
|
Sister chromatid exchange
|
|
Human
Lymphocyte
|
1 umol/L/72H
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 49,6503,1989
|
Sister chromatid exchange
|
|
Human
Fibroblast
|
1 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,317,1978
|
Sister chromatid exchange
|
|
Human
Liver
|
1 mmol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 117,47,1983
|
Mutation in mammalian somatic cells
|
|
Human
Cells - not otherwise specified
|
100 nmol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,765,1980
|
Mutation in mammalian somatic cells
|
|
Human
Fibroblast
|
100 nmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4070,1980
|
Mutation in mammalian somatic cells
|
|
Human
Lymphocyte
|
3 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 128,221,1984
|
Mutation in mammalian somatic cells
|
|
Human
Lymphocyte
|
1200 nmol/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,304,1982
|
Micronucleus test
|
Intraperitoneal
|
Rodent - rat
|
800 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,309,1987
|
Micronucleus test
|
Oral
|
Rodent - rat
|
125 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 278,165,1992
|
Morphological transformation
|
|
Rodent - rat
Cells - not otherwise specified
|
1 mg/L
|
NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 30,303,1983
|
Morphological transformation
|
|
Rodent - rat
Liver
|
100 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,5087,1983
|
DNA damage
|
|
Rodent - rat
Cells - not otherwise specified
|
4 ug/tube
|
BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 24,331,1983
|
Morphological transformation
|
Oral
|
Rodent - rat
|
200 mg/kg
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1157,1980
|
DNA adduct
|
|
Rodent - rat
Lung
|
2 umol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,267,1982
|
Morphological transformation
|
|
Rodent - rat
Embryo
|
15400 ug/L
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,1303,1981
|
DNA adduct
|
Intravenous
|
Rodent - rat
|
140 ug/kg
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 38,4640,1978
|
DNA adduct
|
Administration onto the skin
|
Rodent - rat
|
800 nmol/kg
|
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 28,387,1981
|
DNA adduct
|
Intraperitoneal
|
Rodent - rat
|
40 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 5,231,1984
|
DNA damage
|
|
Rodent - rat
Liver
|
80 umol/L
|
JBCHA3 Journal of Biological Chemistry. (428 E. Preston St., Baltimore, MD 21202) V.1- 1905- Volume(issue)/page/year: 252,6424,1977
|
DNA damage
|
|
Rodent - rat
Fibroblast
|
1500 umol/L
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 18,337,1977
|
DNA adduct
|
|
Rodent - rat
Cells - not otherwise specified
|
1500 nmol/L
|
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 1,3,1980
|
DNA adduct
|
|
Rodent - rat
Cells - not otherwise specified
|
1 umol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 4,297,1983
|
Unscheduled DNA synthesis
|
Oral
|
Rodent - rat
|
240 mg/kg/8D (continuous)
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 218,13,1989
|
DNA damage
|
|
Rodent - rat
Cells - not otherwise specified
|
31 umol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,203,1982
|
Unscheduled DNA synthesis
|
|
Rodent - rat
Liver
|
5 umol/L
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 6,207,1979
|
Unscheduled DNA synthesis
|
|
Rodent - rat
Cells - not otherwise specified
|
100 mmol/L
|
SHKKAN Shika Kiso Igakkai Zasshi. Journal of the Japanese Association for Basic Dentistry. (Shika Kiso Igakkai, Hanayama Bldg., 1-44-2 Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1959- Volume(issue)/page/year: 22,300,1980
|
DNA damage
|
Oral
|
Rodent - rat
|
62500 ug/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,393,1989
|
DNA adduct
|
|
Rodent - rat
Embryo
|
500 ug/L
|
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 25,86,1984
|
DNA inhibition
|
|
Rodent - rat
Liver
|
10 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,337,1985
|
Unscheduled DNA synthesis
|
|
Rodent - rat
Cells - not otherwise specified
|
1 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,361,1990
|
DNA inhibition
|
Intraperitoneal
|
Rodent - rat
|
40 mg/kg
|
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,755,1985
|
DNA adduct
|
|
Rodent - rat
Cells - not otherwise specified
|
5 mg/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 15,661,1994
|
Body fluid assay
|
|
Rodent - rat
Bacteria - Salmonella typhimurium
|
10 mg/kg
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,155,1979
|
Body fluid assay
|
|
Rodent - rat
Ovary
|
2 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 143,263,1985
|
DNA adduct
|
|
Rodent - rat
Liver
|
3 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 419,91,1998
|
Cytogenetic analysis
|
Intravenous
|
Rodent - rat
|
50 mg/kg
|
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 64,637,1973
|
Cytogenetic analysis
|
Intraperitoneal
|
Rodent - rat
|
800 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,309,1987
|
Cytogenetic analysis
|
Unreported
|
Rodent - rat
|
423 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 113,239,1983
|
Cytogenetic analysis
|
|
Rodent - rat
Cells - not otherwise specified
|
100 ug/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 169,141,1986
|
Sister chromatid exchange
|
|
Rodent - rat
Liver
|
1600 pmol/L
|
ECEBDI Experimental Cell Biology. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.44- 1976- Volume(issue)/page/year: 52,355,1984
|
Sister chromatid exchange
|
|
Rodent - rat
Cells - not otherwise specified
|
500 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,409,1982
|
Sister chromatid exchange
|
|
Rodent - rat
Ascites tumor
|
1 mmol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 122,47,1983
|
Sister chromatid exchange
|
Intraperitoneal
|
Rodent - rat
|
25 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,1041,1989
|
Mutation in mammalian somatic cells
|
|
Rodent - rat
Cells - not otherwise specified
|
18850 nmol/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,33,1983
|
Mutation in mammalian somatic cells
|
|
Rodent - rat
Mammary gland
|
1 mg/L
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 70,777,1983
|
Mutation in mammalian somatic cells
|
|
Rodent - rat
Liver
|
1 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 130,53,1984
|
Micronucleus test
|
|
Rodent - mouse
Fibroblast
|
250 ug/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 279,217,1992
|
Micronucleus test
|
Oral
|
Rodent - mouse
|
40 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 234,179,1990
|
Micronucleus test
|
Administration onto the skin
|
Rodent - mouse
|
20 ug/kg
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,163,1991
|
Micronucleus test
|
Intraperitoneal
|
Rodent - mouse
|
30 mg/kg
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,698,1981
|
Mutation in microorganisms
|
|
Rodent - mouse
Lymphocyte
|
250 ug/L
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),103,1988
|
Specific locus test
|
Parenteral
|
Rodent - mouse
|
100 mg/kg
|
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,75,1977
|
Morphological transformation
|
Oral
|
Rodent - mouse
|
100 mg/kg/8D (intermittent)
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 49,1236,1989
|
DNA damage
|
|
Rodent - mouse
Lymphocyte
|
500 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 203,155,1988
|
Morphological transformation
|
|
Rodent - mouse
Cells - not otherwise specified
|
100 ug/L
|
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 4,166,1969
|
Morphological transformation
|
|
Rodent - mouse
Embryo
|
100 ug/L
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 5,659,1985
|
Morphological transformation
|
|
Rodent - mouse
Fibroblast
|
500 ug/L
|
AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 1,133,1980
|
Mutation test systems - not otherwise specified
|
Administration onto the skin
|
Rodent - mouse
|
4 mg/kg
|
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 199,778,1978
|
DNA adduct
|
|
Rodent - mouse
Liver
|
6 umol/L
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 62,947,1979
|
DNA damage
|
|
Rodent - mouse
Fibroblast
|
3 mg/L
|
COINAV Colloques Internationaux du Centre National de la Recherche Scientifique. (Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018) V.1- 1946- Volume(issue)/page/year: 256,389,1977
|
DNA adduct
|
|
Rodent - mouse
Embryo
|
1200 nmol/L
|
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 4,813,1969
|
DNA adduct
|
Administration onto the skin
|
Rodent - mouse
|
40 umol/kg
|
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 23,201,1979
|
Unscheduled DNA synthesis
|
Administration onto the skin
|
Rodent - mouse
|
8 mg/kg
|
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 18,281,1979
|
Unscheduled DNA synthesis
|
Oral
|
Rodent - mouse
|
12 mg/kg
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1547,1984
|
DNA inhibition
|
|
Rodent - mouse
Fibroblast
|
7 umol/L
|
JOUOD4 Journal of UOEH (University of Occupational and Environmental Health). (Univ. of Occupational and Environmental Health, 1-1 Iseigaoka, Yahata-nishi-ku, Kitakyushu 807, Japan) V.1- 1979- Volume(issue)/page/year: 5,147,1983
|
DNA inhibition
|
|
Rodent - mouse
Cells - not otherwise specified
|
100 umol/L
|
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 65,1321,1980
|
DNA inhibition
|
Intraperitoneal
|
Rodent - mouse
|
100 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977
|
Unscheduled DNA synthesis
|
|
Rodent - mouse
Liver
|
1 umol/L
|
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 12,119,1984
|
Mutation test systems - not otherwise specified
|
Administration onto the skin
|
Rodent - mouse
|
200 mg/L
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 4,155,1971/1972
|
Mutation test systems - not otherwise specified
|
Intraperitoneal
|
Rodent - mouse
|
50 mg/kg
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19,259,1992
|
Body fluid assay
|
|
Rodent - mouse
Bacteria - Salmonella typhimurium
|
100 mg/kg
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 38,4478,1978
|
Cytogenetic analysis
|
Intraperitoneal
|
Rodent - mouse
|
50 mg/kg
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19,259,1992
|
Cytogenetic analysis
|
Oral
|
Rodent - mouse
|
25 mg/kg
|
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 3,321,1983
|
Cytogenetic analysis
|
|
Rodent - mouse
Leukocyte
|
100 ug/L/17H (continuous)
|
IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 9,435,1972
|
Cytogenetic analysis
|
|
Rodent - mouse
Fibroblast
|
5 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,1866,1982
|
Cytogenetic analysis
|
|
Rodent - mouse
Lymphocyte
|
2500 ug/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 6),24,1986
|
Sister chromatid exchange
|
|
Rodent - mouse
Lung
|
25 mg/kg
|
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 158,269,1978
|
Sister chromatid exchange
|
|
Rodent - mouse
Embryo
|
1 umol/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 2,245,1980
|
Sister chromatid exchange
|
|
Rodent - mouse
Fibroblast
|
100 nmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,1866,1982
|
Sister chromatid exchange
|
Intraperitoneal
|
Rodent - mouse
|
20 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,1041,1989
|
Sister chromatid exchange
|
Intravenous
|
Rodent - mouse
|
100 mg/kg
|
JJMCAQ Japanese Journal of Medical Science and Biology. (National Institute of Health, 2-chome, Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.5- 1952- Volume(issue)/page/year: 38,207,1985
|
Sister chromatid exchange
|
|
Rodent - mouse
Bone marrow
|
30 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 224,465,1989
|
Sister chromatid exchange
|
|
Rodent - mouse
Cells - not otherwise specified
|
30 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 224,465,1989
|
Dominant lethal test
|
Intraperitoneal
|
Rodent - mouse
|
750 mg/kg
|
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 219,385,1968
|
Mutation in mammalian somatic cells
|
|
Rodent - mouse
Lymphocyte
|
4500 ug/L
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,580,1981
|
Mutation in mammalian somatic cells
|
|
Rodent - mouse
Embryo
|
3 umol/L
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 76,930,1979
|
Mutation in mammalian somatic cells
|
|
Rodent - mouse
Fibroblast
|
200 nmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,1866,1982
|
Host-mediated assay
|
|
Rodent - mouse
Bacteria - Escherichia coli
|
50464 ug/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,83,1990
|
Sperm Morphology
|
Intraperitoneal
|
Rodent - mouse
|
100 mg/kg/5D
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 72,4425,1975
|
Sperm Morphology
|
Parenteral
|
Rodent - mouse
|
500 mg/kg
|
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,75,1977
|
Sperm Morphology
|
Unreported
|
Rodent - mouse
|
200 mg/kg
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,318,1982
|
Micronucleus test
|
|
Rodent - hamster
Embryo
|
100 ug/L
|
CCLCDY Zhonghua Zhongliu Zazhi. Chinese Journal of Oncology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1978- Volume(issue)/page/year: 8,90,1986
|
Mutation in microorganisms
|
|
Rodent - hamster
Embryo
|
4 umol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,419,1989
|
Mutation in microorganisms
|
|
Rodent - hamster
Ovary
|
1 mg/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,354,1982
|
Mutation in microorganisms
|
|
Rodent - hamster
Lung
|
25 nmol/plate
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,2660,1979
|
Specific locus test
|
|
Rodent - hamster
Ovary
|
5 mg/L
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,594,1981
|
DNA repair
|
|
Rodent - hamster
Cells - not otherwise specified
|
1 umol/L
|
TIVIEQ Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 5,511,1991
|
Morphological transformation
|
|
Rodent - hamster
Cells - not otherwise specified
|
1200 nmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2413,1975
|
Morphological transformation
|
|
Rodent - hamster
Lung
|
10 ug/L
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 1000(Sp Iss 1),18,1980
|
Morphological transformation
|
Intraperitoneal
|
Rodent - hamster
|
500 mg/kg
|
ARPAAQ Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50; V.70-99, 1960-75. For publisher information, see APLMAS. Volume(issue)/page/year: 95,380,1973
|
Morphological transformation
|
|
Rodent - hamster
Embryo
|
400 ug/L
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 13,105,1976
|
Morphological transformation
|
|
Rodent - hamster
Kidney
|
80 ug/L
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978
|
Morphological transformation
|
|
Rodent - hamster
Fibroblast
|
1 mg/L
|
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 264,360,1976
|
Morphological transformation
|
Parenteral
|
Rodent - hamster
|
1 mg/L
|
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 56,672,1966
|
DNA damage
|
|
Rodent - hamster
Lung
|
30 umol/L/2H
|
BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,732,1976
|
DNA damage
|
|
Rodent - hamster
Ovary
|
100 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,259,1980
|
DNA adduct
|
|
Rodent - hamster
Embryo
|
500 ug/L
|
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 25,86,1984
|
DNA adduct
|
|
Rodent - hamster
Cells - not otherwise specified
|
800 nmol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,2837,1973
|
Unscheduled DNA synthesis
|
|
Rodent - hamster
Embryo
|
300 ug/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 129,111,1984
|
Mutation test systems - not otherwise specified
|
|
Rodent - hamster
Embryo
|
1 mg/L
|
BICHAW Biochemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1962- Volume(issue)/page/year: 17,1597,1978
|
DNA damage
|
|
Rodent - hamster
Cells - not otherwise specified
|
100 nmol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,1283,1982
|
DNA adduct
|
|
Rodent - hamster
Cells - not otherwise specified
|
1 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,4723,1983
|
Unscheduled DNA synthesis
|
|
Rodent - hamster
Liver
|
10 umol/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,1,1983
|
Unscheduled DNA synthesis
|
|
Rodent - hamster
Cells - not otherwise specified
|
100 ug/L
|
EVSRBT Environmental Science Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1972- Volume(issue)/page/year: 27,277,1983
|
Unscheduled DNA synthesis
|
|
Rodent - hamster
Lung
|
6 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 230,111,1990
|
Phage inhibition capacity
|
|
Rodent - hamster
Embryo
|
60 ug/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 6,474,1984
|
DNA inhibition
|
|
Rodent - hamster
Cells - not otherwise specified
|
150 umol/L
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 53,163,1990
|
DNA damage
|
|
Rodent - hamster
Fibroblast
|
10 umol/L
|
LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 48,1255,1991
|
DNA adduct
|
|
Rodent - hamster
Cells - not otherwise specified
|
5 mg/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 15,661,1994
|
Cytogenetic analysis
|
|
Rodent - hamster
Ovary
|
3970 nmol/L
|
MOTOEX Molecular Toxicology. (Taylor & Francis, Inc., 242 Cherry St., Philadelphia, PA USA 19106) V.1- 1987- Volume(issue)/page/year: 1,217,1987
|
Cytogenetic analysis
|
Inhalation
|
Rodent - hamster
|
100 ug/L/5D (intermittent)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 1,139,1981
|
Cytogenetic analysis
|
Intraperitoneal
|
Rodent - hamster
|
200 mg/kg
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 2,277,1978
|
Cytogenetic analysis
|
|
Rodent - hamster
Lung
|
100 mg/L
|
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978- Volume(issue)/page/year: 4,41,1980
|
Cytogenetic analysis
|
|
Rodent - hamster
Fibroblast
|
1 mg/L
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 30,103,1974
|
Sister chromatid exchange
|
Intraperitoneal
|
Rodent - hamster
|
900 mg/kg/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 66,65,1979
|
Sister chromatid exchange
|
|
Rodent - hamster
Ovary
|
5610 nmol/L
|
MOTOEX Molecular Toxicology. (Taylor & Francis, Inc., 242 Cherry St., Philadelphia, PA USA 19106) V.1- 1987- Volume(issue)/page/year: 1,217,1987
|
Sister chromatid exchange
|
|
Rodent - hamster
Embryo
|
10 ng/L
|
CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 17,221,1983
|
Sister chromatid exchange
|
|
Rodent - hamster
Lung
|
1 ug/L
|
JCINAO Journal of Clinical Investigation. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1924- Volume(issue)/page/year: 64,1245,1979
|
Sister chromatid exchange
|
|
Rodent - hamster
Fibroblast
|
500 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,409,1982
|
Sister chromatid exchange
|
Inhalation
|
Rodent - hamster
|
100 ug/L/5D (intermittent)
|
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: DE83-007112
|
Sister chromatid exchange
|
Unreported
|
Rodent - hamster
|
25 mg/kg
|
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 33,25,1977
|
Sister chromatid exchange
|
|
Rodent - hamster
Cells - not otherwise specified
|
9900 nmol/L
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 6,1627,1985
|
Sex chromosome loss and nondisjunction
|
|
Rodent - hamster
Liver
|
1 mg/L
|
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 5,397,1985
|
Sister chromatid exchange
|
|
Rodent - hamster
Liver
|
110 ug/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 207,69,1988
|
Mutation in mammalian somatic cells
|
Intraperitoneal
|
Rodent - hamster
|
200 mg/kg
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 2,277,1978
|
Mutation in mammalian somatic cells
|
|
Rodent - hamster
Lung
|
1 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 113,499,1983
|
Mutation in mammalian somatic cells
|
|
Rodent - hamster
Fibroblast
|
1 mg/L
|
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 264,360,1976
|
Mutation in mammalian somatic cells
|
|
Rodent - hamster
Embryo
|
500 ug/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1445,1984
|
Sperm Morphology
|
Intraperitoneal
|
Rodent - hamster
|
25 mg/kg/5D
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 8,929,1981
|
Cytogenetic analysis
|
|
Rodent - hamster
Ovary
|
1 mmol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 111,209,1983
|
Morphological transformation
|
|
Rodent - guinea pig
Cells - not otherwise specified
|
10 mg/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1035,1975
|
DNA adduct
|
|
Primate - monkey
Lung
|
25 umol/L
|
50NNAZ "Polynuclear Aromatic Hydrocarbons, International Symposium, 7th, 1982," Cooke, M., and A.J. Dennis, eds., Columbus, OH, Battelle Press, 1983 Volume(issue)/page/year: 7,845,1983
|
DNA adduct
|
|
Primate - monkey
Cells - not otherwise specified
|
1 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,4723,1983
|
DNA adduct
|
|
Primate - monkey
Cells - not otherwise specified
|
25 umol/L
|
50NNAZ "Polynuclear Aromatic Hydrocarbons, International Symposium, 7th, 1982," Cooke, M., and A.J. Dennis, eds., Columbus, OH, Battelle Press, 1983 Volume(issue)/page/year: 7,845,1983
|
Unscheduled DNA synthesis
|
|
Primate - monkey
Liver
|
10 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,91,1988
|
Sister chromatid exchange
|
|
Primate - monkey
Kidney
|
1 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,3626,1985
|
Micronucleus test
|
Multiple routes
|
Amphibian - frog
|
60 ppb
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,12,1989
|
DNA adduct
|
Intravenous
|
Rodent - rabbit
|
1 mg/kg
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 51,151,1984
|
DNA damage
|
Intraperitoneal
|
Amphibian - frog
|
125 gm/kg
|
STEVA8 Science of the Total Environment. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1972- Volume(issue)/page/year: 32,13,1983
|
DNA adduct
|
Intraperitoneal
|
Rodent - rabbit
|
11 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,1405,1982
|
DNA adduct
|
|
Mammal - species unspecified
Lymphocyte
|
30 umol/L
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 47,87,1983
|
DNA damage
|
|
Mammal - species unspecified
Kidney
|
1 mmol/L
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 6,333,1980
|
Unscheduled DNA synthesis
|
Administration onto the skin
|
Rodent - rabbit
|
100 ug/L
|
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 21,94,1980
|
DNA adduct
|
|
Mammal - dog
Cells - not otherwise specified
|
1 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,4723,1983
|
DNA adduct
|
|
Mammal - dog
Lung
|
1 umol/L
|
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,4723,1983
|
Cytogenetic analysis
|
Parenteral
|
Bird - chicken
|
31 ug/kg
|
47JMAE "Cytogenetic Assays of Environmental Mutagens," Hsu, T.C., ed., Totowa, NJ, Allanheld, Osmun & Co., 1982 Volume(issue)/page/year: -,137,1982
|
Sister chromatid exchange
|
Administration onto the skin
|
Rodent - rabbit
|
30 ug/L
|
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 21,94,1980
|
Sister chromatid exchange
|
|
Rodent - rabbit
Lymphocyte
|
10 umol/L/30M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,321,1978
|
Sister chromatid exchange
|
Parenteral
|
Bird - chicken
|
31 ug/kg
|
47JMAE "Cytogenetic Assays of Environmental Mutagens," Hsu, T.C., ed., Totowa, NJ, Allanheld, Osmun & Co., 1982 Volume(issue)/page/year: -,137,1982
|
Sister chromatid exchange
|
Multiple routes
|
Amphibian - frog
|
10 mg/L
|
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 6),30,1986
|
Mutation in mammalian somatic cells
|
Oral
|
Rodent - mouse
|
1750 mg/kg
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 164,1,2001
|
Sister chromatid exchange
|
|
Human
Lymphocyte
|
0.03 mg/L/24H
|
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 39,485,2001
|
Heritable translocation test
|
Administration onto the skin
|
Insect - Drosophila melanogaster
|
2 mmol/L/48H
|
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 39,485,2001
|
DNA damage
|
Intraperitoneal
|
Rodent - mouse
|
150 mg/kg/3D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 480-481,147,2001
|
DNA adduct
|
|
Human
Fibroblast
|
50 umol/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 484,3,2001
|
DNA adduct
|
Oral
|
Human
|
0.1 ug/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 472,119,2000
|
Micronucleus test
|
|
Human
Liver
|
4 mg/L/1H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 490,1,2001
|
DNA damage
|
|
Human
Liver
|
5 mg/L/1H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 490,1,2001
|
DNA adduct
|
|
Human
Fibroblast
|
0.1 mmol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 471,57,2000
|
DNA adduct
|
|
Human
Mammary gland
|
0.08 umol/L/12H
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 155,47,2000
|
Specific locus test
|
|
Human
Cells - not otherwise specified
|
15 ug/L/10H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 472,93,2000
|
DNA adduct
|
Intratracheal
|
Rodent - rat
|
10 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,87,2000
|
DNA adduct
|
Administration onto the skin
|
Rodent - rat
|
10 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,87,2000
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
2 ug/plate/72H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 116,189,2000
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
5 ug/plate/20M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 492,13,2001
|
DNA adduct
|
Intraperitoneal
|
Rodent - mouse
|
13.200 mg/kg
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 21,629,2000
|
Mutation in mammalian somatic cells
|
Intraperitoneal
|
Rodent - rat
|
120 mg/kg/3D
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 21,715,2000
|
DNA adduct
|
Oral
|
Rodent - mouse
|
7840 mg/kg/2W (continuous)
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 21,1601,2000
|
DNA damage
|
Intraperitoneal
|
Rodent - mouse
|
500 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 493,39,2001
|
DNA adduct
|
|
Rodent - hamster
Embryo
|
1 mg/L/6H
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 22,1505,2001
|
Sperm Morphology
|
|
Human
Sperm
|
200 mg/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 491,57,2001
|
Micronucleus test
|
|
Rodent - hamster
Cells - not otherwise specified
|
1 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 491,87,2001
|
Mutation in mammalian somatic cells
|
Intraperitoneal
|
Rodent - mouse
|
32.3 mg/kg/8D (intermittent)
|
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 137,137,1999
|
Micronucleus test
|
|
Human
Cells - not otherwise specified
|
0.2 mg/L/28H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 495,89,2001
|
Specific locus test
|
|
Human
Lymphocyte
|
0.1 mg/L/72H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 495,157,2001
|
DNA damage
|
|
Bacteria - Escherichia coli
|
24.1 ug/L/3H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 515,85,2002
|
Specific locus test
|
|
Rodent - hamster
Cells - not otherwise specified
|
0.5 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 517,135,2002
|
Cytogenetic analysis
|
|
Rodent - hamster
Fibroblast
|
0.01 gm/L/48H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 16,183,2001
|
Phage inhibition capacity
|
|
Bacteria - Escherichia coli
|
0.5 umol/L
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 36,206,2000
|
DNA adduct
|
|
Human
Mammary gland
|
1 umol/L/24H
|
CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 13,10,2000
|
DNA damage
|
|
Human
Mammary gland
|
1 umol/L/4H
|
CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 13,10,2000
|
DNA damage
|
|
Human
Mammary gland
|
1 umol/L/24H
|
CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 13,10,2000
|
Sister chromatid exchange
|
|
Rodent - hamster
Lung
|
5 mg/L/6H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 515,181,2002
|
DNA damage
|
|
Rodent - rat
Liver
|
5 umol/L/12H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 519,163,2002
|
DNA damage
|
|
Human
Liver
|
10 umol/L/12H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 519,163,2002
|
DNA damage
|
|
Rodent - hamster
Lung
|
0.1 umol/L/1H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 17,45,2002
|
DNA adduct
|
|
Rodent - hamster
Lung
|
0.5 umol/L/6H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 17,45,2002
|
DNA adduct
|
Oral
|
Rodent - mouse
|
273 mg/kg/7W
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 16,333,2001
|
Morphological transformation
|
|
Rodent - mouse
Fibroblast
|
0.033 umol/L/21D
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 35,300,2000
|
Cytogenetic analysis
|
|
Human
Sperm
|
200 mg/L/120M
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 504,183,2002
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
6.125 nmol/plate/20M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 519,133,2002
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
10 mg/L/48H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 520,161,2002
|
DNA damage
|
|
Bacteria - Escherichia coli
|
1000 ng/plate/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 520,161,2002
|
Sister chromatid exchange
|
|
Rodent - hamster
Ovary
|
20 mg/L/4H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 520,161,2002
|
DNA damage
|
|
Fish - not otherwise specified
Embryo
|
10 mg/L/16H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 513,83,2002
|
Micronucleus test
|
Administration onto the skin
|
Rodent - rat
|
1 pph/3D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 513,93,2002
|
Micronucleus test
|
Administration onto the skin
|
Rodent - mouse
|
0.5 pph/3D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 513,93,2002
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
10 ug/plate/20M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 514,19,2002
|
Specific locus test
|
|
Rodent - hamster
Ovary
|
1 mg/L/9D
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 16,260,1990
|
DNA adduct
|
Oral
|
Rodent - mouse
|
6.3 mg/kg/9W (intermittent)
|
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 15,59,1995
|
Micronucleus test
|
Oral
|
Rodent - mouse
|
6.3 mg/kg/9W (intermittent)
|
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 15,59,1995
|
Unscheduled DNA synthesis
|
Oral
|
Rodent - mouse
|
6.3 mg/kg/9W (intermittent)
|
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 15,59,1995
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.001 umol/plate/20M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 521,187,2002
|
DNA damage
|
|
Rodent - mouse
Fibroblast
|
1 umol/L/19H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 521,91,2002
|
DNA adduct
|
|
Rodent - mouse
Fibroblast
|
4 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 521,91,2002
|
DNA damage
|
|
Human
Liver
|
3.67 mmol/L/20H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 536,79,2003
|
Micronucleus test
|
|
Human
Liver
|
0.5 umol/L/20H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 536,79,2003
|
DNA damage
|
Intratracheal
|
Rodent - rat
|
750 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 534,33,2003
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.0015 mmol/L/20M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 508,147,2002
|
Specific locus test
|
|
Rodent - hamster
Lung
|
4 mg/L/3H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 537,183,2003
|
Morphological transformation
|
|
Rodent - hamster
Embryo
|
2.5 mg/L/4H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 537,183,2003
|
Micronucleus test
|
|
Rodent - hamster
Ovary
|
0.1 mg/L/4H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 537,115,2003
|
DNA repair
|
|
Microorganism - not otherwise specified
|
1 mmol/L
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,227,2003
|
Host-mediated assay
|
|
Rodent - rat
Bacteria - Salmonella typhimurium
|
40 mg/kg
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 72,315,2003
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
40 nmol/plate/48H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 541,123,2003
|
Micronucleus test
|
|
Rodent - mouse
Mammary gland
|
1.77 mg/L/3H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 540,153,2003
|
DNA repair
|
Intraperitoneal
|
Rodent - mouse
|
10 mg/kg
|
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 109,71,2001
|
DNA repair
|
|
Human
Mammary gland
|
5 umol/L/48H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 39,235,2002
|
Cytogenetic analysis
|
|
Human
Mammary gland
|
5 umol/L/24H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 39,235,2002
|
DNA damage
|
Intratracheal
|
Rodent - rat
|
3.75 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 538,19,2003
|
DNA adduct
|
|
Bacteria - Salmonella typhimurium
|
30 ug/plate/1H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 40,1,2002
|
Specific locus test
|
Oral
|
Rodent - mouse
|
625 mg/kg/11D (intermittent)
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 559,199,2004
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
1 mg/L
|
MAERE* Marine Environmental Research. (Kidlington, Oxford : Elsevier) V. 1- 1978- Volume(issue)/page/year: 53,243,2002
|
DNA damage
|
|
Human
Lymphocyte
|
300 umol/L/20M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 557,203,2004
|
DNA damage
|
|
Human
Liver
|
1 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 557,167,2004
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
1 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 557,167,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.5 nmol/plate/48H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 557,99,2004
|
DNA damage
|
|
Human
Ascites tumor
|
25 umol/L/24H
|
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 40,1077,2002
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
4 mg/L/72H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 558,181,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.02 umol/plate/72H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 558,93,2004
|
DNA damage
|
|
Human
Lymphocyte
|
0.05 mmol/L/3H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 540,43,2003
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
25 umol/L/24H
|
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 23,273,2003
|
DNA adduct
|
|
Rodent - rat
Liver
|
0.1 mg/L/1H
|
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 67,1711,2004
|
DNA adduct
|
|
Mammal - cattle
Cells - not otherwise specified
|
10 mmol/L/60M
|
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 139,129,2002
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
Embryo
|
19.8 nmol/plate/72H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 545,11,2004
|
Morphological transformation
|
|
Rodent - hamster
Embryo
|
1 mg/L/7D
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 142,77,2003
|
DNA damage
|
|
Rodent - hamster
Embryo
|
1 mg/L/5H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 142,77,2003
|
Micronucleus test
|
Oral
|
Rodent - mouse
|
320 mg/kg/4W (intermittent)
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 144,183,2003
|
DNA adduct
|
|
Rodent - rat
Ascites tumor
|
1 umol/L/24H
|
ETOPFR Environmental Toxicology and Pharmacology (Elsevier Science, P.O.Box 7247-7682,Philadelphia,PA 19170 -7682,USA OR Elsevier Science B.V.,P.O.Box 1270,1000 BG Amsterdam,The Netherlands) V.1- Feb.1996- Volume(issue)/page/year: 12,15,2002
|
Specific locus test
|
Oral
|
Rodent - mouse
|
50 mg/kg
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 14,113,1999
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
10 mg/L/3H
|
RTOPDW Regulatory Toxicology and Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 37,11,2003
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
2 ug/plate/48H
|
RTOPDW Regulatory Toxicology and Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 35,255,2002
|
Mutation in mammalian somatic cells
|
|
Rodent - hamster
Ovary
|
2 mg/L/5H
|
RTOPDW Regulatory Toxicology and Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 35,255,2002
|
DNA adduct
|
|
Human
Lymphocyte
|
1 umol/L/1H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 582,155,2005
|
DNA damage
|
|
Human
Liver
|
25 umol/L/24H
|
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 23(Suppl 1),273,2003
|
Micronucleus test
|
|
Human
Liver
|
25 umol/L/24H
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 198,315,2004
|
DNA adduct
|
Oral
|
Mammal - species unspecified
|
87.5 mg/kg/7D (intermittent)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,195,2005
|
DNA damage
|
|
Mammal - pig
Cells - not otherwise specified
|
50 umol/L/24H
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 207,255,2005
|
Micronucleus test
|
|
Mammal - pig
Cells - not otherwise specified
|
100 umol/L/30H
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 207,255,2005
|
Micronucleus test
|
Intraperitoneal
|
Rodent - mouse
|
75 mg/kg/3D (intermittent)
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 45,44,2005
|
DNA adduct
|
Oral
|
Rodent - rat
|
2523 ug/kg
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,305,2005
|
DNA damage
|
Administration onto the skin
|
Rodent - mouse
|
2 gm/L/3D (continuous)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,448,2005
|
DNA adduct
|
|
Human
Fibroblast
|
100 nmol/L
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 44,465,2005
|
DNA adduct
|
|
Human
Cells - not otherwise specified
|
1 nmol/L/24H
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 91,333,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
10 mg/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 578,225,2005
|
Micronucleus test
|
Administration onto the skin
|
Rodent - mouse
|
48 mg/kg/3D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 588,58,2005
|
Specific locus test
|
Administration onto the skin
|
Rodent - mouse
|
56 mg/kg/8W (continuous)
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 588,35,2005
|
Morphological transformation
|
|
Rodent - mouse
Embryo
|
0.5 mg/L/2D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 588,7,2005
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
1 umol/L/16H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 46,126,2005
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.4 umol/L/48H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 46,126,2005
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
4 umol/L/2H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 46,126,2005
|
DNA damage
|
|
Bacteria - Salmonella typhimurium
|
4 umol/L/2H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 46,126,2005
|
DNA adduct
|
Subcutaneous
|
Rodent - mouse
|
25 mg/kg/5W (intermittent)
|
JAPTO* Journal of Applied Toxicology (John Wiley & Sons, Ltd., Oldlands Way Bognor Regis West Sussex, PO22 9SA England) V.1- 1981- Volume(issue)/page/year: 23,255,2003
|
DNA adduct
|
Oral
|
Rodent - mouse
|
37.5 mg/kg/30D (intermittent)
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 78,347,2004
|
DNA damage
|
|
Human
Mammary gland
|
0.12 mg/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 588,47,2005
|
DNA damage
|
|
Bacteria - Salmonella typhimurium
|
1.25 umol/L/125M
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 43,10,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.4 mg/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 578,210,2005
|
Mutation in microorganisms
|
|
Bacteria - Escherichia coli
|
0.5 mg/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 588,166,2005
|
Morphological transformation
|
|
Rodent - hamster
Embryo
|
33.4 ug/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 572,45,2005
|
Cytogenetic analysis
|
|
Rodent - mouse
Cells - not otherwise specified
|
2.1 umol/L
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,368,2002
|
DNA damage
|
|
Rodent - mouse
Cells - not otherwise specified
|
1 umol/L
|
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 66,368,2002
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
25 umol/L /20H
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 213,138,2005
|
Unscheduled DNA synthesis
|
|
Human
Cells - not otherwise specified
|
0.1 umol/L /20H
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 213,138,2005
|
Micronucleus test
|
|
Human
Cells - not otherwise specified
|
2 umol/L /20H
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 213,138,2005
|
Mutation in microorganisms
|
|
Yeast - Saccharomyces cerevisiae
|
200 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577S,1,2005
|
Specific locus test
|
|
Rodent - mouse
Fibroblast
|
1 umol/L/5W
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577S,1,2005
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
1 ug/plate
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577S,1,2005
|
Host-mediated assay
|
Multiple routes
|
Fish - not otherwise specified
|
10 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577S,1,2005
|
Specific locus test
|
Intratracheal
|
Rodent - mouse
|
20 mg/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577S,1,2005
|
Cytogenetic analysis
|
|
Human
Embryo
|
0.1 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 604,8,2006
|
DNA damage
|
|
Human
Embryo
|
50 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 604,8,2006
|
Micronucleus test
|
|
Rodent - mouse
Cells - not otherwise specified
|
4 mg/L/4H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 47,56,2006
|
Specific locus test
|
Multiple routes
|
Fish - not otherwise specified
|
10 mg/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577S,1,2005
|
Micronucleus test
|
|
Human
Cells - not otherwise specified
|
50 umol/L/1H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 159,83,2005
|
DNA damage
|
|
Human
Ovary
|
9 umol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 575,17,2005
|
Mutation in mammalian somatic cells
|
|
Rodent - hamster
Ovary
|
25 mg/L/3H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 20,29,2005
|
Specific locus test
|
|
Rodent - hamster
Ovary
|
4 mg/L/5H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 602,14,2006
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
1.25 ug/plate/60H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 19,245,2004
|
Micronucleus test
|
|
Human
Mammary gland
|
1 umol/L/24H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 21,351,2006
|
Unscheduled DNA synthesis
|
Intratracheal
|
Rodent - rat
|
3.75 mg/kg
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 18,449,2003
|
DNA repair
|
Intratracheal
|
Rodent - rat
|
3.75 mg/kg
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 18,449,2003
|
Mutation test systems - not otherwise specified
|
|
Rodent - rat
Liver
|
1 umol/L/48H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 615,87,2007
|
DNA adduct
|
|
Human
Lung
|
1 umol/L/24H
|
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 91,333,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
45.9 pmol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 626,88,2007
|
Mutation in microorganisms
|
|
Microorganism - not otherwise specified
|
0.1 mg/L/4H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 611,17,2006
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
8 nmol/plate/73H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 629,122,2007
|
Micronucleus test
|
|
Rodent - hamster
Ovary
|
44.4 umol/L/3H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 630,1,2007
|
Micronucleus test
|
|
Human
Liver
|
50 umol/L/1H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 159,83,2005
|
DNA damage
|
|
Rodent - rat
Liver
|
5 umol/L/2H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 164,54,2006
|
DNA damage
|
|
Rodent - rat
Lung
|
1 umol/L/2H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 164,54,2006
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
20 umol/L/30M
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 627,136,2007
|
Mutation in microorganisms
|
|
Yeast - Saccharomyces cerevisiae
|
26 mg/L/16H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 20,105,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.1 ug/plate
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 609,60,2006
|
DNA damage
|
Oral
|
Rodent - mouse
|
125 mg/kg
|
HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 24,149,2005
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
5 umol/L/4H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 42,228,2003
|
DNA adduct
|
Oral
|
Rodent - mouse
|
5 mg/kg
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 42,243,2003
|
Cytogenetic analysis
|
Subcutaneous
|
Rodent - mouse
|
20 mg/kg
|
BPBLEO Biological and Pharmaceutical Bulletin. (Pharmaceutical Society of Japan, 2-12-15-201 Shibuya Shibuya-ku, Tokyo 150, Japan) V.16- 1993- Volume(issue)/page/year: 28,2063,2005
|
Micronucleus test
|
Subcutaneous
|
Rodent - mouse
|
20 mg/kg
|
BPBLEO Biological and Pharmaceutical Bulletin. (Pharmaceutical Society of Japan, 2-12-15-201 Shibuya Shibuya-ku, Tokyo 150, Japan) V.16- 1993- Volume(issue)/page/year: 28,2063,2005
|
DNA adduct
|
|
Human
Mammary gland
|
0.25 umol/L/6H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 20,469,2005
|
DNA adduct
|
|
Human
Liver
|
0.25 umol/L/6H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 20,469,2005
|
Specific locus test
|
Multiple routes
|
Fish - not otherwise specified
|
50 ppb/24H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 46,88,2005
|
Unscheduled DNA synthesis
|
|
Human
Liver
|
0.01 umol/L/44H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 559,211,2004
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
3 ug/plate/48H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 609,68,2006
|
Micronucleus test
|
Multiple routes
|
Non-mammalian species
|
101 ng/L/4D (continuous)
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 649,135,2008
|
DNA damage
|
Multiple routes
|
Non-mammalian species
|
1993 ng/L/168H (continuous)
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 649,135,2008
|
DNA damage
|
|
Human
Fibroblast
|
1 umol/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 547,109,2004
|
DNA adduct
|
Intraperitoneal
|
Rodent - mouse
|
625 mg/kg/5D (intermittent)
|
NSAPCC Naunyn-Schmiedeberg's Archives of Pharmacology. (Springer Verlag, Heidelberger, Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.272- 1972- Volume(issue)/page/year: 375(Suppl 1),73,2007
|
DNA damage
|
|
Human
Lung
|
2 umol/L/2H
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 174,10,2007
|
DNA damage
|
|
Rodent - hamster
Fibroblast
|
50 umol/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 650,96,2008
|
DNA damage
|
|
Rodent - hamster
Fibroblast
|
10 umol/L/2H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 650,96,2008
|
Cytogenetic analysis
|
|
Human
Lymphocyte
|
5 mg/L/2H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 47,150,2006
|
DNA adduct
|
|
Rodent - rat
Liver
|
30 umol/L/24H
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 22,55,2007
|
Mutation in microorganisms
|
|
Bacteria - Salmonella typhimurium
|
0.1 ug/plate/12H
|
JTEHF8 Journal of Toxicology and Environmental Health, Part A. (Taylor & Francis, 47 Runway Rd., Suite G, Levittown, PA 19057) V.53- 1998- Volume(issue)/page/year: 68,1841,2005
|
Cytogenetic analysis
|
|
Rodent - hamster
Ovary
|
20 mg/L/24H
|
JTEHF8 Journal of Toxicology and Environmental Health, Part A. (Taylor & Francis, 47 Runway Rd., Suite G, Levittown, PA 19057) V.53- 1998- Volume(issue)/page/year: 68,1841,2005
|
DNA adduct
|
Oral
|
Rodent - mouse
|
819 mg/kg/13W (continuous)
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 24,613,2003
|
DNA adduct
|
Administration onto the skin
|
Rodent - mouse
|
8 mg/kg/4D (intermittent)
|
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 25,493,2004
|
DNA adduct
|
Administration onto the skin
|
Rodent - mouse
|
404 ug/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 649,161,2008
|
Specific locus test
|
Administration onto the skin
|
Rodent - mouse
|
404 ug/kg
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 649,161,2008
|
Morphological transformation
|
|
Rodent - hamster
Embryo
|
5 mg/L/7D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 548,1,2004
|
DNA damage
|
Multiple routes
|
Non-mammalian species
|
1 mg/L/24H
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 654,69,2008
|
DNA damage
|
Multiple routes
|
Non-mammalian species
|
10 mg/L/3D
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 654,69,2008
|
DNA adduct
|
Multiple routes
|
Fish - not otherwise specified
|
5 ppm/24H
|
EMS37* Environmental Mutagen Society 37th Annual Meeting Abstracts. Poster Session Abstracts. Poster Session I Volume(issue)/page/year: -,411,2006
|
DNA adduct
|
Multiple routes
|
Fish - not otherwise specified
|
10 ppm/4H
|
EMS37* Environmental Mutagen Society 37th Annual Meeting Abstracts. Poster Session Abstracts. Poster Session I Volume(issue)/page/year: -,411,2006
|
DNA adduct
|
|
Human
Lung
|
1 umol/L/18H
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 48,14,2007
|
DNA damage
|
|
Human
Cells - not otherwise specified
|
5 umol/L/30M
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 48,106,2007
|
|
|
|
ACGIH TLV-Control as low as possible
|
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,2007
|
ACGIH TLV-Suspected human carcinogen
|
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,2007
|
IARC Cancer Review:Animal Sufficient Evidence
|
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,91,1973
|
IARC Cancer Review:Animal Sufficient Evidence
|
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,211,1983
|
IARC Cancer Review:Human No Adequate Data
|
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,211,1983
|
IARC Cancer Review:Group 2A
|
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 558,7,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 566,21,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 558,155,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 540,89,2003
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 544,397,2003
|
TOXICOLOGY REVIEW
|
PEXTAR Progress in Experimental Tumor Research. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1960- Volume(issue)/page/year: 5,157,1964
|
TOXICOLOGY REVIEW
|
85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer Congress," Chicago, Year Book Medical Pub., 1971 Volume(issue)/page/year: 5,257,1970
|
TOXICOLOGY REVIEW
|
85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972
|
TOXICOLOGY REVIEW
|
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: CONF-691001
|
TOXICOLOGY REVIEW
|
BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 24,129,1983
|
TOXICOLOGY REVIEW
|
PVTMA3 Preventive Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1972- Volume(issue)/page/year: 9,622,1980
|
TOXICOLOGY REVIEW
|
ARPTDI Annual Review of Pharmacology and Toxicology. (Annual Reviews, Inc., POB 10139, Palo Alto, CA 94303) V.16- 1976- Volume(issue)/page/year: 43,309,2003
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 127,47,2002
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 128,55,2002
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 134,39,2002
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 133,1,2002
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 134,31,2002
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 140-141,311,2003
|
TOXICOLOGY REVIEW
|
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 140-141,353,2003
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 567,227,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 567,109,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 567,401,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 567,151,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 567,347,2004
|
TOXICOLOGY REVIEW
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 197,173,2004
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 14,301,1999
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 17,149,2002
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 14,141,1999
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 15,431,2000
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 15,431,2000
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 15,431,2000
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 589,208,2005
|
TOXICOLOGY REVIEW
|
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 197,49,2004
|
TOXICOLOGY REVIEW
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 45,100,2005
|
TOXICOLOGY REVIEW
|
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 45,106,2005
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 577,146,2005
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 588,88,2005
|
TOXICOLOGY REVIEW
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 20,441,2005
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 567,427,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 566,209,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 613,103,2006
|
TOXICOLOGY REVIEW
|
NETOX* NeuroToxicology (Amsterdam : Elsevier Science) V.1- 1979- Volume(issue)/page/year: 26,573,2005
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 20,399,2005
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 613,76,2006
|
TOXICOLOGY REVIEW
|
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005 Volume(issue)/page/year: -,257,2005
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 614,77,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 628,31,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 628,31,2007
|
TOXICOLOGY REVIEW
|
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 44,1699,2006
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 627,10,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 627,59,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 635,90,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 584,1,2005
|
TOXICOLOGY REVIEW
|
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005 Volume(issue)/page/year: -,334,2005
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 636,95,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 658,28,2008
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 566,183,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 547,1,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 533,92,2003
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 658,124,2008
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 540,165,2003
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 658,154,2008
|
TOXICOLOGY REVIEW
|
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 23,428,2007
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 658,271,2008
|
TOXICOLOGY REVIEW
|
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 19,423,2004
|
TOXICOLOGY REVIEW
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 659,202,2008
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U.S. STANDARDS AND REGULATIONS |
- OSHA PEL (Gen Indu):8H TWA 0.2 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994
- OSHA PEL (Construc):8H TWA 0.2 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994
- OSHA PEL (Shipyard):8H TWA 0.2 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993
- OSHA PEL (Fed Cont):8H TWA 0.2 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994
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OCCUPATIONAL EXPOSURE LIMITS |
- OEL-AUSTRALIA: Carcinogen, JAN1993
- OEL-AUSTRIA: TRK 0.002 mg/m3, JAN 2006
- OEL-AUSTRIA: TRK 0.005 mg/m3, JAN 2006
- OEL-BELGIUM: Carcinogen, JAN1993
- OEL-FINLAND: TWA 0.01 mg/m3, Skin, Carcinogen, JAN1999
- OEL-NORWAY: TWA 0.04 mg/m3, JAN1999
- OEL-POLAND: TWA 0.003 mg/m3, JAN1999
- OEL-RUSSIA: TWA 0.00015 mg/m3, Carcinogen, JUN2003
- OEL-SWEDEN: TWA 0.002 mg/m3;STEL 0.02 mg/m3, Skin, Carcinogen, JUN2005
- OEL-SWITZERLAND: MAK-W 0.0002 ppm (0.002 mg/m3), Carcinogen, DEC2006
- OEL IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
- OEL IN SINGAPORE, VIETNAM check ACGIH TLV
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- ATSDR TOXICOLOGY PROFILE
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB/95/264370
- EPA GENETOX PROGRAM 1988, Positive: Body fluid assay; Carcinogenicity-mouse/rat
- EPA GENETOX PROGRAM 1988, Positive: Cell transform.-SA7/F344 rat; SHE-focus assay
- EPA GENETOX PROGRAM 1988, Positive: Cell transform.-mouse embryo
- EPA GENETOX PROGRAM 1988, Positive: Cell transform.-mouse prostate
- EPA GENETOX PROGRAM 1988, Positive: Cell transform.-RLV F344 rat embryo
- EPA GENETOX PROGRAM 1988, Positive: Cell transform.-SA7/SHE; Host-mediated assay
- EPA GENETOX PROGRAM 1988, Positive: L5178Y cells in vitro-TK test; Mammalian micronucleus
- EPA GENETOX PROGRAM 1988, Positive: Mouse spot test; E coli polA with S9
- EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
- EPA GENETOX PROGRAM 1988, Positive: In vitro SCE-human lymphocytes; In vitro SCE-human
- EPA GENETOX PROGRAM 1988, Positive: Sperm morphology-mouse; D melanogaster Sex-linked lethal
- EPA GENETOX PROGRAM 1988, Positive: In vitro UDS in rat liver; V79 cell culture-gene mutation
- EPA GENETOX PROGRAM 1988, Positive/dose response: Cell transform.-BALB/c-3T3; SHE-clonal assay
- EPA GENETOX PROGRAM 1988, Positive/dose response: Cell transform.-C3H/10T1/2
- EPA GENETOX PROGRAM 1988, Positive/dose response: In vitro SCE-nonhuman; In vivo SCE-nonhuman
- EPA GENETOX PROGRAM 1988, Negative: D melanogaster-nondisjunction
- EPA GENETOX PROGRAM 1988, Negative: Rodent heritable translocation; Mouse specific locus
- EPA GENETOX PROGRAM 1988, Negative: UDS in mouse germ cells; S cerevisiae-homozygosis
- EPA GENETOX PROGRAM 1988, Inconclusive: E coli polA without S9; In vitro UDS-human fibroblast
- EPA GENETOX PROGRAM 1988, Positive: CHO gene mutation
- EPA TSCA Section 8(b) CHEMICAL INVENTORY
- EPA TSCA Section 8(d) unpublished health/safety studies
- On EPA IRIS database
- EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
- NIOSH Analytical Method, 1994: Polynuclear aromatic hydrocarbons by HPLC, 5506; by GC, 5515
- NTP 11th Report on Carcinogens,2004:Reasonably anticipated to be a human carcinogen
- OSHA ANALYTICAL METHOD #ID-58
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- RTECS® is provided quarterly by MDL Information Systems, Inc. and was last updated: 2008-11.
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